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UBC Okanagan study suggests ditching cheat days on diet

Researchers argue that those on keto diets should reconsider cheat days
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The often embraced 害羞草研究所榗heat day害羞草研究所 is a common theme in many diets and the popular ketogenic diet is no exception.

New research from UBC害羞草研究所檚 Okanagan campus says that just one 75-gram dose of glucose害羞草研究所攖he equivalent a large bottle of soda or a plate of fries害羞草研究所攚hile on a high fat, low carbohydrate diet can lead to damaged blood vessels.

害羞草研究所淭he ketogenic害羞草研究所攐r keto害羞草研究所攄iet has become very common for weight loss or to manage diseases like type 2 diabetes,害羞草研究所 said Jonathan Little, associate professor in the School of Health and Exercise Sciences at UBCO and study senior author.

害羞草研究所淚t consists of eating foods rich in fats, moderate in protein, but very low in carbohydrates and it causes the body to go into a state called ketosis.害羞草研究所

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Little said that the diet can be very effective because once the body is in ketosis and starved for its preferred fuel glucose, the body害羞草研究所檚 chemistry changes and it begins to aggressively burn its fat stores. This leads to weight loss and can reverse the symptoms of diseases like Type 2 diabetes.

害羞草研究所淲e were interested in finding out what happens to the body害羞草研究所檚 physiology once a dose of glucose is reintroduced,害羞草研究所 says Cody Durrer, UBC Okanagan doctoral student and study first author.

害羞草研究所淪ince impaired glucose tolerance and spikes in blood sugar levels are known to be associated with an increased risk in cardiovascular disease, it made sense to look at what was happening in the blood vessels after a sugar hit.害羞草研究所

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For the test, the researchers recruited nine healthy young males and had them consume a 75-gram glucose drink before and after a seven-day high fat, low carbohydrate diet. The diet consisted of 70 per cent fat, 10 per cent carbohydrates and 20 per cent protein, similar to that of a modern ketogenic diet.

害羞草研究所淲e were originally looking for things like an inflammatory response or reduced tolerance to blood glucose,害羞草研究所 says Durrer. 害羞草研究所淲hat we found instead were biomarkers in the blood suggesting that vessel walls were being damaged by the sudden spike in glucose.害羞草研究所

Little said that the most likely culprit for the damage is the body害羞草研究所檚 own metabolic response to excess blood sugar, which causes blood vessel cells to shed and possibly die.

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害羞草研究所淓ven though these were otherwise healthy young males, when we looked at their blood vessel health after consuming the glucose drink, the results looked like they might have come from someone with poor cardiovascular health,害羞草研究所 adds Little. 害羞草研究所淚t was somewhat alarming.害羞草研究所

The researchers point out that with only nine individuals included in the study, more work is needed to verify their findings, but that the results should give those on a keto diet pause when considering a cheat day.

害羞草研究所淥ur data suggests a ketogenic diet is not something you do for six days a week and take Saturday off.害羞草研究所

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