The clinical trial of a drug that one expert says looks 害羞草研究所渧ery promising害羞草研究所� for use in stopping the progression of COVID-19 moved into a new phase this week, with the opportunity to participate now open to all eligible patients in the Fraser Health region.

Dr. Gregory Haljan 害羞草研究所� head of Surrey Memorial Hospital害羞草研究所檚 critical care unit and Fraser Health害羞草研究所檚 regional medical director for research 害羞草研究所� said Monday (April 26) that around 300 COVID-19-positive patients are sought to receive the medication bamlanivimab as part of the B-EPIC (Bamlanivimab-Emergency Passive Immunity in COVID-19) study.

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Designed in January, the study aims to determine if the antibody can prevent those who get COVID-19 from getting so sick they need to be hospitalized 害羞草研究所� and if it can, 害羞草研究所渨ell, we really need that right now,害羞草研究所� Haljan said.

害羞草研究所淲e害羞草研究所檙e in the third wave,害羞草研究所� Haljan said of the pandemic. 害羞草研究所淭his is the worst it害羞草研究所檚 been (in the SMH intensive care unit) yet. We害羞草研究所檙e working about as hard as we can right now in the ICU.

害羞草研究所淭his third wave has been a real kick in the pants.害羞草研究所�

Researchers also want to learn if bamlanivimab can reduce the long-term effects of the illness.

Its use for COVID-19 treatment in high-risk patients has interim approval from Health Canada. The drug is designed to block the COVID-19 virus from attaching to and entering cells, thus potentially preventing the illness from worsening in newly diagnosed patients.

害羞草研究所淥nce you get an infection, it害羞草研究所檚 too late for a vaccine to work,害羞草研究所� Haljan said. 害羞草研究所淲hat we want to do is provide those antibodies (that a vaccine typically triggers a body to produce) early in the disease, to give the immune system a head start.害羞草研究所�

Recruiting for the study opened in March to residents of Surrey, White Rock and Delta. It then expanded to include patients living in Burnaby, Langley, Maple Ridge and Pitt Meadows.

Haljan said participants must begin the therapy within three days of a positive COVID-19 test, or within 10 days of their first symptoms.

Eligible participants are those 65 and older, or between 18 and 64 years old who have tested positive for COVID-19 and have at least one illness or condition that puts them at risk of being hospitalized for COVID-19 infection.

Haljan hopes to recruit up to 20 patients per day over the next two weeks, in order to complete the study by May 9.

Currently, the medication is being delivered at an infusion clinic set up at Peace Arch Hospital, but Haljan said the hope is to establish more clinics this week, particularly in the Fraser East area.

He emphasized that while the medication only has interim approval, it is 害羞草研究所渧ery safe,害羞草研究所� and, it has been found to 害羞草研究所渞etain activity害羞草研究所� against the U.K variant of COVID-19; the most prevalent variant in Canada.

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The study, he noted, 害羞草研究所渋s asking questions nobody else in the world is asking right now about this drug.害羞草研究所�

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